GabaDown is a patient advocacy resource — not a clinical service. Based on the patient's intake and published deprescribing guidelines, GabaDown produces a draft taper framework the patient brings to you for review and approval. You stay the clinical decision-maker. GabaDown does the structural work a 15-minute appointment doesn't have time for.
We are clear with every patient about the boundaries of this resource before they engage. Your clinical role is not replaced or diminished.
GabaDown draws on peer-reviewed evidence for its taper frameworks and supplement information. The key publications informing this resource:
| Publication | Relevance |
|---|---|
| Horowitz MA & Taylor DM. The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs. Wiley-Blackwell, 2024. | First major clinical guideline to address gabapentinoids specifically. Basis for hyperbolic tapering concepts referenced in patient journals — the position that receptor occupancy follows a hyperbolic curve, so reduction steps should get smaller as dose decreases. |
| Mersfelder TL & Nichols WH. Gabapentin: Abuse, Dependence, and Withdrawal. Ann Pharmacother, 2016. | Established that withdrawal symptoms are more likely at daily doses over 1,800mg — foundational to GabaDown's focus on long-term high-dose users specifically. |
| JAGS case study, 2025. Patient-directed gabapentin taper in an older adult. | Documents improved mental clarity, mobility, and medication burden following a patient-initiated, supervised reduction — directly mirrors the GabaDown client profile. |
| McDonald EG et al. Patient empowerment brochures to increase gabapentinoid deprescribing: the GABA-WHY trial. CMAJ Open, 2022. | Showed patient education materials doubled gabapentinoid deprescribing rates (21.1% vs 9.9%). GabaDown is a deeper, personalized version of this kind of patient education intervention. |
| Strahan AE et al. Trends in Dispensed Gabapentin Prescriptions in the United States, 2010 to 2024. Ann Intern Med, 2025. | Documents the scale of long-term gabapentin use and rising prescribing rates — contextualising the patient population GabaDown serves. |
Each journal is built from a detailed intake questionnaire and delivered within 7 days. Everything is tailored to the patient's starting dose, history, and the method you've recommended.
Three steps. No forms on your end. No clinical liability — GabaDown is a patient-initiated resource that works alongside your care.
If you have questions about GabaDown's clinical framing, want to discuss a specific patient situation, or are interested in a deeper conversation about the resource — reach out directly.
Email is the best way to reach us. We respond to all provider enquiries within 24 hours. If you want to share GabaDown with a patient directly, gabadown.com is the patient-facing entry point.
hello@gabadown.comClinical disclaimer: GabaDown is a patient advocacy and personal support resource. It is not a medical service, does not employ clinicians, and nothing on this website or in any GabaDown journal constitutes medical advice, diagnosis, or treatment. GabaDown requires that all clients have a doctor who is aware of and supportive of their reduction plan before beginning. All taper decisions remain the responsibility of the prescribing physician and pharmacist. GabaDown does not advocate for any specific tapering method and follows whatever approach the prescribing physician recommends.
For clinical emergencies, patients are directed to their doctor and local emergency services. GabaDown is not an emergency service.